Podcasting is all the rage right now. I use Power MP3 Recorder on my laptop with a Y-connector to my phone to record. While I thought the recording was the challenge. It's not. The challenge is in wrapping the podcast is a professional package with lead-in music and intro as well as closing music and notes. You can tell the difference between a polished podcast and the amateur kind.
I've noticed that recordings of conference calls have poor quality as well. Lots of things affect the quality of a conference call. For example, if you call into a conference bridge via a cell phone, Skype or a VoIP line, there tends to be a quality issue, especially if the bridge is VoIP. I have had people dial in to a bridge while driving with the window down. People have put the conference on hold resulting in a soundtrack for the call from that company's on-hold music (or worse recording). When the sound quality of the recording is poor, it affects the product.
After you get through post production of the podcast, there are 3 factors left: hosting, distribution and marketing.
Get on iTunes. Utilize an RSS feed. Take advantage of the 20+ podcast directories. Blog about it and list it on your website (use a text link). Add it to your newsletter. Marketing is telling people about it. From the podcasts I have heard, a couple of hundred listeners is medium sized. Just get your story out there.
Hosting requires a lot of storage and bandwidth. The average podcast I have seen is about 40MB. One hundred people listen weekly you have pushed 16GB in a month.
BTW, you can thank the iPod for making podcasts more mainstream. WIthout the advent of the MP3 player going mainstream, podcasts would still be by and for geeks.